Semaglutide Side Effects

Warning: Risk of Thyroid C-Cell TumorsIn rodents, semaglutide causes thyroid C-cell tumors. It is unknown whether semaglutide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as the human relevance of semaglutide-induced rodent thyroid C-cell tumors has not been determined.Semaglutide is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk of MTC and symptoms of thyroid tumors

Serious side effects of Semaglutide

Along with its needed effects, semaglutide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking semaglutide:

More common

  • Anxiety
  • bloating
  • blurred vision
  • chills
  • cold sweats
  • confusion
  • constipation
  • cool, pale skin
  • cough
  • darkened urine
  • depression
  • diarrhea
  • difficulty swallowing
  • dizziness
  • fast heartbeat
  • fever
  • headache
  • increased hunger
  • indigestion
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • nausea
  • nervousness
  • nightmare
  • pain in the stomach, side, or abdomen, possibly radiating to the back
  • seizures
  • skin rash
  • slurred speech
  • tightness in the chest
  • trouble breathing
  • unusual tiredness or weakness
  • vomiting
  • yellow eyes or skin

Other side effects of Semaglutide

Some side effects of semaglutide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Acid or sour stomach
  • belching
  • excess air or gas in stomach
  • feeling pressure in the stomach
  • heartburn
  • passing gas
  • stomach discomfort, swelling, tenderness, or upset

Common (1% to 10%): Hypotension, orthostatic hypotension

Uncommon (0.1% to 1%): Syncope

Frequency not reported: Increased heart rate

Dermatologic

Common (1% to 10%): Hair loss